Sugi Predict

Sugi Predict / Compounds / SCHEMBL285020

SCHEMBL285020

SCHEMBL285020

NCCCCCC(=O)C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 4/20 0.64
▸ THRB P10828 2/20 0.64
▸ KMT2A Q03164 2/20 0.64
▸ MEN1 O00255 1/20 0.64
▸ ALDH1A1 P00352 1/20 0.64
▸ PLG P00747 1/20 0.64
▸ ALOX15 P16050 1/20 0.64
▸ SLC6A2 P23975 1/20 0.64
▸ RECQL P46063 1/20 0.64
▸ SLC6A3 Q01959 1/20 0.64
▸ NFKB1 P19838 2/20 0.59
▸ CYP2D6 P10635 1/20 0.59
▸ BLM P54132 3/20 0.56
▸ NPSR1 Q6W5P4 2/20 0.56
▸ PAOX Q6QHF9 1/20 0.54
▸ TSHR P16473 3/20 0.48
▸ GABRR3 A8MPY1 1/20 0.48
▸ GABRP O00591 1/20 0.48
▸ GABRD O14764 1/20 0.48
▸ HDAC3 O15379 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2059628 1.00 LMNA (0.64) LMNATHRBKMT2AMEN1ALDH1A1
SCHEMBL2368877 1.00 LMNA (0.64) LMNATHRBKMT2AMEN1ALDH1A1
SCHEMBL728991 0.97 NFKB1 (0.62) LMNATHRBKMT2AMEN1ALDH1A1
SCHEMBL728986 0.89 — —
Hydrochloric Acid SCHEMBL28408226 0.86 BLM (0.57) LMNATHRBKMT2AMEN1ALDH1A1
SCHEMBL31390042 0.86 LMNA (0.65) LMNATHRBKMT2AMEN1ALDH1A1
SCHEMBL10962384 0.86 OR51E2 (0.56) LMNAKMT2AMEN1ALDH1A1ALOX15
SCHEMBL10961559 0.86 OR51E2 (0.56) LMNAKMT2AMEN1ALDH1A1ALOX15
SCHEMBL10957816 0.86 OR51E2 (0.56) LMNAKMT2AMEN1ALDH1A1ALOX15
SCHEMBL10964715 0.86 OR51E2 (0.56) LMNAKMT2AMEN1ALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230022727-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID GENOMATICA INC (US) 2023-01-26 — — US claimed
US-20190330670-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID AGAIN BIO APS (DK) 2019-10-31 — — US claimed
US-20130303723-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID AGAIN BIO APS (DK) 2013-11-14 — — US claimed
WO-2012177721-A1 MICROORGANISMS FOR PRODUCING 6-AMINOCAPROIC ACID GENOMATICA, INC. (US) 2012-12-27 — — WO claimed
EP-2427544-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID Genomatica, Inc. (US) 2012-03-14 — — EP claimed
US-20100317069-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID AGAIN BIO APS (DK) 2010-12-16 — — US claimed
WO-2010129936-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID GENOMATICA, INC. (US) 2010-11-11 — — WO claimed
US-12577591-B2 Microorganisms and methods for increasing co-factors GENOMATICA, INC. (US) 2026-03-17 — — US disclosed
US-20260028651-A1 METHOD OF PRODUCING & PROCESSING DIAMINES AGAIN BIO APS (DK) 2026-01-29 — — US disclosed
US-12503711-B2 Method of producing and processing diamines to a diamine free base using a carbonate intermediate and an engineered microorganism GENOMATICA, INC. (US) 2025-12-23 — — US disclosed
CN-114728871-B Microorganisms and methods for reducing byproducts 基因组股份公司 2024-12-27 — — CN disclosed
CN-118853644-A Method for producing 6-carbon nylon monomer by utilizing microorganisms 东华大学 2024-10-29 — — CN disclosed
US-20240182935-A1 METHOD OF PRODUCING & PROCESSING DIAMINES AGAIN BIO APS (DK) 2024-06-06 — — US disclosed
WO-2012177721-A1 MICROORGANISMS FOR PRODUCING 6-AMINOCAPROIC ACID GENOMATICA, INC. (US) 2012-12-27 — — WO disclosed
US-20120301950-A1 BIOLOGICAL SYNTHESIS OF DIFUNCTIONAL HEXANES AND PENTANES FROM CARBOHYDRATE FEEDSTOCKS CELEXION, LLC 2012-11-29 — — US disclosed
US-20120282661-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID GENOMATICA, INC. (US) 2012-11-08 — — US disclosed
EP-2427544-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID Genomatica, Inc. (US) 2012-03-14 — — EP disclosed
US-20100317069-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID AGAIN BIO APS (DK) 2010-12-16 — — US disclosed
WO-2010129936-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID GENOMATICA, INC. (US) 2010-11-11 — — WO disclosed
US-4384137-A CATALYTIC OXIDATION WITH CUPRIC IONS SOCIETE FRANCAISE HOECHST (FR) 1983-05-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260028651-A1 METHOD OF PRODUCING & PROCESSING DIAMINES DDC, DAO, ODC1 LMNA 2536/4885THRB 311/4885KMT2A 1633/4885
US-12577591-B2 Microorganisms and methods for increasing co-factors ABAT, HADHB, MMAB LMNA 1752/4885THRB 587/4885KMT2A 1724/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.