Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2376239 | 0.83 | ENPP2 (0.72) | ENPP2PTGS2 | |
| SCHEMBL8122557 | 0.76 | ENPP2 (0.56) | ENPP2PTGS2 | |
| SCHEMBL7677302 | 0.75 | PTGS2 (0.62) | ENPP2PTGS2 | |
| SCHEMBL10300269 | 0.75 | PTGS2 (0.62) | ENPP2PTGS2 | |
| SCHEMBL17548700 | 0.75 | ENPP2 (0.62) | ENPP2PTGS2 | |
| Water SCHEMBL27483474 | 0.74 | ENPP2 (0.54) | ENPP2PTGS2 | |
| SCHEMBL28182477 | 0.72 | GAA (0.65) | ENPP2PTGS2 | |
| SCHEMBL517832 | 0.72 | ENPP2 (0.59) | ENPP2PTGS2 | |
| SCHEMBL12807 | 0.72 | GAA (0.65) | ENPP2PTGS2 | |
| Water SCHEMBL17653839 | 0.70 | GAA (0.62) | ENPP2PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117185972-B | Preparation method of florfenicol intermediate | 苏州开元民生科技股份有限公司 | 2024-02-13 | — | — | CN | claimed |
| CN-117185972-A | Preparation method of florfenicol intermediate | 苏州开元民生科技股份有限公司 | 2023-12-08 | — | — | CN | claimed |
| CN-109678811-B | Asymmetric preparation method of florfenicol intermediate cyclic compound | 湖北中牧安达药业有限公司 | 2020-12-29 | — | — | CN | claimed |
| CN-117185972-B | Preparation method of florfenicol intermediate | 苏州开元民生科技股份有限公司 | 2024-02-13 | — | — | CN | disclosed |
| CN-117185972-B | Preparation method of florfenicol intermediate | 苏州开元民生科技股份有限公司 | 2024-02-13 | — | — | CN | disclosed |
| CN-117185972-A | Preparation method of florfenicol intermediate | 苏州开元民生科技股份有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-117185972-A | Preparation method of florfenicol intermediate | 苏州开元民生科技股份有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-109678811-B | Asymmetric preparation method of florfenicol intermediate cyclic compound | 湖北中牧安达药业有限公司 | 2020-12-29 | — | — | CN | disclosed |