Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 3/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27708876 | 0.88 | RXRA (0.44) | RXRARXRBACHEPTGS1KMT2A | |
| SCHEMBL8053572 | 0.84 | RXRA (0.47) | RXRARXRBACHEPTGS1KMT2A | |
| SCHEMBL2737262 | 0.83 | KDM4E (0.49) | RXRARXRBACHEPTGS1KMT2A | |
| SCHEMBL2968363 | 0.80 | RXRA (0.53) | RXRARXRBKMT2AMEN1GAA | |
| SCHEMBL19171565 | 0.80 | ACHE (0.46) | RXRARXRBACHEPTGS1KMT2A | |
| SCHEMBL14122063 | 0.80 | RXRA (0.44) | RXRARXRBACHEPTGS1KMT2A | |
| SCHEMBL1416897 | 0.80 | RXRA (0.44) | RXRARXRBACHEPTGS1KMT2A | |
| SCHEMBL28503154 | 0.80 | DRD1 (0.44) | RXRAPTGS1KMT2AMEN1HTT | |
| SCHEMBL14157496 | 0.80 | RXRA (0.44) | RXRARXRBACHEPTGS1KMT2A | |
| SCHEMBL6055421 | 0.80 | RXRA (0.47) | RXRARXRBACHEPTGS1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127212-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |