Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.43 |
| ▸ | EHMT1 | Q9H9B1 | 2/20 | 0.43 |
| ▸ | CDC25B | P30305 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | APAF1 | O14727 | 2/20 | 0.42 |
| ▸ | TDP2 | O95551 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | GLS | O94925 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | TERT | O14746 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487827 | 0.97 | POLB (0.48) | POLBCASP3KMT2AMEN1EHMT2 | |
| SCHEMBL6135716 | 0.85 | CES1 (0.47) | POLBCASP3KMT2AMEN1EHMT2 | |
| SCHEMBL22651544 | 0.80 | DPP4 (0.43) | POLBCASP3KMT2AMEN1EHMT2 | |
| SCHEMBL21449882 | 0.77 | GSTP1 (0.40) | POLBKMT2AMEN1KDM4ENPC1 | |
| SCHEMBL28160078 | 0.77 | POLB (0.64) | POLBCASP3KMT2AMEN1EHMT2 | |
| SCHEMBL2022462 | 0.77 | POLB (0.64) | POLBCASP3KMT2AMEN1EHMT2 | |
| SCHEMBL21099252 | 0.75 | ERCC1 (0.63) | KMT2AMEN1CYP1A2KDM4ECES2 | |
| SCHEMBL4694772 | 0.74 | ALDH1A1 (0.43) | POLBCASP3CDC25BCYP1A2KDM4E | |
| SCHEMBL21921317 | 0.74 | POLB (0.43) | POLBKMT2AMEN1CYP1A2APAF1 | |
| SCHEMBL23254941 | 0.74 | HTR1A (0.50) | POLBKMT2AMEN1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112105385-A | IRAK degrading agents and uses thereof | 凯麦拉医疗公司 | 2020-12-18 | — | — | CN | disclosed |