Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 9/20 | 0.50 |
| ▸ | CA1 | P00915 | 8/20 | 0.50 |
| ▸ | CA9 | Q16790 | 7/20 | 0.50 |
| ▸ | CA4 | P22748 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 8/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.44 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | LOX | P28300 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2852244 | 0.91 | MAPT (0.48) | MAPTMEN1KMT2A | |
| SCHEMBL2859374 | 0.90 | MAPT (0.52) | CA2CA1CA9CA4MAPT | |
| SCHEMBL2852372 | 0.89 | MAPT (0.48) | CA2CA1CA9CA4MAPT | |
| SCHEMBL2859712 | 0.87 | CA1 (0.45) | CA2CA1CA9CA4MAPT | |
| SCHEMBL2853065 | 0.87 | NR3C1 (0.46) | MAPTMEN1KMT2A | |
| SCHEMBL2848317 | 0.86 | MAPT (0.46) | MAPTMEN1KMT2A | |
| SCHEMBL2860975 | 0.86 | MAPT (0.49) | MAPTMEN1KMT2AKDR | |
| SCHEMBL2850524 | 0.85 | MAPT (0.43) | MAPTMEN1KMT2AEPHX2 | |
| SCHEMBL2848538 | 0.84 | MAPT (0.45) | MAPT | |
| SCHEMBL2861576 | 0.84 | MAPT (0.45) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |