Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 5/20 | 0.48 |
| ▸ | CA2 | P00918 | 5/20 | 0.48 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
| ▸ | CA4 | P22748 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 4/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2861572 | 0.92 | CA1 (0.49) | CA1CA2CA7CA4CA9 | |
| SCHEMBL2855798 | 0.91 | MAPT (0.45) | MAPTCA1CA2CA7CA4 | |
| SCHEMBL2855767 | 0.91 | P2RX1 (0.47) | MAPTCA1CA2CA7CA4 | |
| SCHEMBL2856585 | 0.90 | CA1 (0.44) | CA1CA2CA7CA9CA12 | |
| SCHEMBL2854610 | 0.90 | KEAP1 (0.45) | MAPTCA1CA2CA7CA4 | |
| SCHEMBL2859466 | 0.89 | MAPT (0.46) | MAPTCA1CA2CA7CA4 | |
| SCHEMBL2854620 | 0.89 | CA1 (0.43) | CA1CA2CA9CA12LMNA | |
| SCHEMBL2850385 | 0.89 | CA2 (0.50) | MAPTCA1CA2CA7CA4 | |
| SCHEMBL2863249 | 0.89 | LMNA (0.48) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL2852249 | 0.88 | MAPT (0.43) | MAPTCA1CA2CA7CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |