Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2858063 | 0.88 | MAPT (0.57) | MAPTRAB9ANPC1NPSR1MAPK14 | |
| SCHEMBL2856078 | 0.85 | KDM4E (0.50) | MAPTMAPK14SMN1; SMN2TSHRPOLB | |
| SCHEMBL2860252 | 0.81 | MAPT (0.39) | KMT2AMEN1MAPTFFAR2MAPK14 | |
| SCHEMBL2854169 | 0.80 | MAPT (0.56) | KMT2AMEN1MAPTRAB9ANPC1 | |
| SCHEMBL2857105 | 0.80 | MAPT (0.56) | KMT2AMEN1MAPTRAB9ANPC1 | |
| SCHEMBL2852152 | 0.80 | MAPT (0.56) | KMT2AMEN1MAPTRAB9ANPC1 | |
| SCHEMBL2855981 | 0.79 | MAPT (0.60) | KMT2AMEN1MAPTRAB9ANPC1 | |
| SCHEMBL2850518 | 0.77 | MAPT (0.48) | MAPTRAB9ANPC1NPSR1MAPK14 | |
| SCHEMBL2860712 | 0.76 | MAPT (0.47) | KMT2AMEN1MAPTRAB9ANPC1 | |
| SCHEMBL2858205 | 0.75 | RAB9A (0.49) | KMT2AMEN1MAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |