Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2858063 | 0.86 | MAPT (0.57) | RAB9ANPC1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL2851938 | 0.82 | SPR (0.56) | RAB9ANPC1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL2852970 | 0.81 | DRD2 (0.51) | KMT2ACNR1 | |
| SCHEMBL2854169 | 0.79 | MAPT (0.56) | RAB9ANPC1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL2853075 | 0.78 | HPGD (0.57) | RAB9ANPC1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL2855981 | 0.78 | MAPT (0.60) | RAB9ANPC1MAPTNPSR1EPHX2 | |
| SCHEMBL10366974 | 0.77 | HSD11B1 (0.56) | RAB9ANPC1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL2850703 | 0.77 | CNR1 (0.56) | RAB9AGAANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL2859857 | 0.76 | CNR1 (0.55) | GAASMN1; SMN2ALDH1A1MAPTKMT2A | |
| SCHEMBL2872664 | 0.76 | MALT1 (0.42) | RAB9ANPC1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |