Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 2/20 | 0.83 |
| ▸ | CA2 | P00918 | 3/20 | 0.64 |
| ▸ | CA1 | P00915 | 2/20 | 0.64 |
| ▸ | CA12 | O43570 | 1/20 | 0.64 |
| ▸ | CA6 | P23280 | 1/20 | 0.64 |
| ▸ | CA5A | P35218 | 1/20 | 0.64 |
| ▸ | CA7 | P43166 | 1/20 | 0.64 |
| ▸ | CA9 | Q16790 | 1/20 | 0.64 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.64 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.64 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.55 |
| ▸ | F10 | P00742 | 1/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.54 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.54 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1937574 | 0.91 | PRMT1 (1.00) | PRMT1CA2CA1CYP19A1ALDH1A1 | |
| SCHEMBL5034890 | 0.87 | PRMT1 (0.77) | PRMT1CYP19A1ALDH1A1TDP1MAPK1 | |
| SCHEMBL6804085 | 0.86 | PRMT1 (0.88) | PRMT1CA2CA1CA12CA6 | |
| SCHEMBL31174173 | 0.85 | PRMT1 (0.73) | PRMT1CA2CA1CA12CA9 | |
| SCHEMBL1565027 | 0.85 | PRMT1 (0.73) | PRMT1CA2CA1CA12CA9 | |
| SCHEMBL2850433 | 0.84 | MAPK1 (0.65) | PRMT1CA2CA1CA12CA6 | |
| SCHEMBL2858653 | 0.83 | PRMT1 (0.75) | PRMT1CYP19A1ALDH1A1AKR1C3 | |
| SCHEMBL28022032 | 0.81 | PRMT1 (0.68) | PRMT1CA2CA1CA12CA9 | |
| SCHEMBL25699504 | 0.80 | PRMT1 (0.70) | PRMT1CA2CA1CYP19A1ALDH1A1 | |
| SCHEMBL452006 | 0.80 | PRMT1 (0.66) | PRMT1CA2CA1CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |