Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 2/20 | 0.75 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.67 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.59 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CCR2 | P41597 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1937574 | 0.86 | PRMT1 (1.00) | PRMT1AKR1C3CYP19A1ALDH1A1 | |
| SCHEMBL1287386 | 0.83 | AKR1C3 (0.70) | PRMT1AKR1C3ALDH1A1TP53 | |
| SCHEMBL2850435 | 0.83 | PRMT1 (0.83) | PRMT1AKR1C3CYP19A1ALDH1A1 | |
| SCHEMBL4672142 | 0.83 | AKR1C3 (0.70) | PRMT1AKR1C3TBXA2RALDH1A1 | |
| SCHEMBL2858650 | 0.82 | AKR1C3 (0.80) | PRMT1AKR1C3TBXA2RALDH1A1 | |
| SCHEMBL31174173 | 0.81 | PRMT1 (0.73) | PRMT1CYP19A1ALDH1A1 | |
| SCHEMBL1565027 | 0.81 | PRMT1 (0.73) | PRMT1CYP19A1ALDH1A1 | |
| SCHEMBL25699504 | 0.81 | PRMT1 (0.70) | PRMT1AKR1C3CYP19A1ALDH1A1 | |
| SCHEMBL30822635 | 0.80 | ALDH1A1 (0.66) | PRMT1AKR1C3CYP19A1TBXA2RALDH1A1 | |
| SCHEMBL17974009 | 0.80 | ALDH1A1 (0.66) | PRMT1AKR1C3CYP19A1TBXA2RALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |