Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 2/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.66 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2850435 | 0.91 | PRMT1 (0.83) | PRMT1ALDH1A1AKR1C3CYP19A1HSD17B10 | |
| SCHEMBL5034890 | 0.87 | PRMT1 (0.77) | PRMT1ALDH1A1AKR1C3CYP19A1TDP1 | |
| SCHEMBL2858653 | 0.86 | PRMT1 (0.75) | PRMT1ALDH1A1AKR1C3CYP19A1 | |
| SCHEMBL1565027 | 0.85 | PRMT1 (0.73) | PRMT1ALDH1A1CYP19A1HSD17B10CA1 | |
| SCHEMBL31174173 | 0.85 | PRMT1 (0.73) | PRMT1ALDH1A1CYP19A1HSD17B10CA1 | |
| SCHEMBL5032445 | 0.84 | CYP19A1 (0.85) | PRMT1ALDH1A1CYP19A1HDAC2HDAC8 | |
| SCHEMBL31339948 | 0.84 | CYP19A1 (0.85) | PRMT1ALDH1A1CYP19A1HDAC2HDAC8 | |
| SCHEMBL412302 | 0.84 | ALDH1A1 (0.79) | PRMT1ALDH1A1AKR1C3HSD17B10CA1 | |
| SCHEMBL4616767 | 0.83 | ALDH1A1 (0.71) | PRMT1ALDH1A1AKR1C3HSD17B10HDAC2 | |
| SCHEMBL6804085 | 0.83 | PRMT1 (0.88) | PRMT1ALDH1A1HSD17B10CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2330904-A2 | 4-ALKYL-SUBSTITUTED DIAMINOPYRIMIDINES | Bayer CropScience AG (DE) | 2011-06-15 | — | — | EP | disclosed |
| WO-2010025863-A2 | 4-ALKYL-SUBSTITUTED DIAMINOPYRIMIDINES | BAYER CROPSCIENCE AG (DE) | 2010-03-11 | — | — | WO | disclosed |