Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | SCD | O00767 | 3/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL623489 | 0.91 | NPSR1 (0.37) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL29256020 | 0.77 | — | — | |
| SCHEMBL15353222 | 0.74 | HTR1A (0.30) | SLC6A4SLC6A2HTR1A | |
| SCHEMBL20836421 | 0.73 | SLC6A4 (0.38) | SLC6A4SLC6A2SLC6A3SCDHTR1A | |
| SCHEMBL1965366 | 0.73 | — | — | |
| SCHEMBL164522 | 0.71 | — | — | |
| SCHEMBL2974066 | 0.71 | L3MBTL1 (0.37) | — | |
| SCHEMBL28716072 | 0.70 | PDE4A (0.33) | SLC6A2SLC6A3HTR1A | |
| SCHEMBL16467697 | 0.70 | MCHR1 (0.34) | SLC6A2SLC6A3HTR1A | |
| SCHEMBL2469196 | 0.68 | PDE4A (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108026067-B | 6-amino-quinoline-3-carbonitriles as COT modulators | 吉利德科学公司 | 2021-01-12 | — | — | CN | disclosed |