SCHEMBL16467697

SCHEMBL16467697

COc1[c]cccc1OC1CC1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCHR1 Q99705 1/20 0.34
HRH1 P35367 2/20 0.33
PDE4B Q07343 3/20 0.33
HTR1A P08908 3/20 0.33
PDE4A P27815 2/20 0.33
PDE4D Q08499 2/20 0.33
ADRA2A P08913 2/20 0.33
ADRA2B P18089 2/20 0.33
ADRA2C P18825 2/20 0.33
PDE10A Q9Y233 2/20 0.33
PDE4C Q08493 1/20 0.33
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA4 P22748 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32
CA14 Q9ULX7 1/20 0.32
LPAR1 Q92633 1/20 0.32
LPAR5 Q9H1C0 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2469198 0.93 PDE4A (0.40) MCHR1PDE4BPDE4APDE4DPDE4C
SCHEMBL15352714 0.83 HTR1A (0.35) MCHR1HRH1HTR1AADRA2AADRA2B
SCHEMBL2469196 0.79 PDE4A (0.40) PDE4BPDE4APDE4DPDE4C
SCHEMBL7599057 0.79 HTR1A (0.34) MCHR1HRH1PDE4BHTR1APDE4A
SCHEMBL123985 0.78 CA1 (0.48) ADRA2BCA12CA1CA2CA4
SCHEMBL15353225 0.78 MCHR1 (0.36) MCHR1HRH1HTR1AADRA2AADRA2B
SCHEMBL28053410 0.77 CA1 (0.46) ADRA2BCA12CA1CA2CA4
SCHEMBL27272029 0.75 CA1 (0.44) ADRA2BCA12CA1CA2CA4
SCHEMBL28716072 0.75 PDE4A (0.33) HRH1PDE4BHTR1APDE4APDE4D
SCHEMBL2461793 0.74 ALDH1A1 (0.42) CA12CA1CA2CA4CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2841429-B1 TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES SUMITOMO CHEMICAL CO (JP) 2020-10-21 EP disclosed
US-10077254-B2 Tetrazolinone compound and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-09-18 US disclosed
EP-3059233-B1 TETRAZOLINONE COMPOUND AND APPLICATION FOR SAME SUMITOMO CHEMICAL CO (JP) 2017-12-20 EP disclosed
US-9565856-B2 Tetrazolinone compounds and its use as pesticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-02-14 US disclosed
US-20160272622-A1 TETRAZOLINONE COMPOUND AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-09-22 US disclosed
EP-3059233-A1 TETRAZOLINONE COMPOUND AND APPLICATION FOR SAME Sumitomo Chemical Company, Limited (JP) 2016-08-24 EP disclosed
US-20150051171-A1 TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-02-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10077254-B2 Tetrazolinone compound and use thereof MT-CO1, UQCRB, MT-CO2 MCHR1 1316/4885HRH1 388/4885PDE4B 4289/4885
US-20150051171-A1 TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES CBR3, CYCS, CBR1 MCHR1 584/4885HRH1 120/4885PDE4B 3749/4885
US-20160272622-A1 TETRAZOLINONE COMPOUND AND USE THEREOF MT-CO1, UQCRB, MT-CO2 MCHR1 1316/4885HRH1 388/4885PDE4B 4289/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.