Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.33 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.33 |
| ▸ | ILK | Q13418 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23161990 | 0.90 | KCNH2 (0.38) | ADORA3KCNH2ALDH1A1PKMP2RX7 | |
| SCHEMBL28503510 | 0.89 | ADORA3 (0.40) | ADORA3KCNH2ALDH1A1PKMGUCY1A1 | |
| SCHEMBL23161934 | 0.86 | ALDH1A1 (0.40) | ADORA3KCNH2ALDH1A1PKMP2RX7 | |
| SCHEMBL28496288 | 0.85 | GUCY1A1 (0.42) | P2RX7IDO1TBXA2RGUCY1A1GUCY1B1 | |
| SCHEMBL23162034 | 0.84 | ADORA3 (0.37) | ADORA3KCNH2ALDH1A1PKMP2RX7 | |
| SCHEMBL23186726 | 0.84 | ADORA3 (0.41) | ADORA3KCNH2P2RX7TLR7IDO1 | |
| SCHEMBL28507122 | 0.84 | ADORA3 (0.48) | ADORA3KCNH2ALDH1A1GUCY1A1GUCY1B1 | |
| SCHEMBL23161989 | 0.83 | KCNH2 (0.45) | ADORA3KCNH2ALDH1A1PKMIDO1 | |
| SCHEMBL23186716 | 0.83 | KCNH2 (0.57) | ADORA3KCNH2P2RX7TLR7GUCY1A1 | |
| SCHEMBL28498467 | 0.81 | ALDH1A1 (0.39) | ADORA3ALDH1A1PKMP2RX7TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108727340-B | Fluorine substituted indazoles and use thereof | 广东东阳光药业有限公司 | 2020-12-29 | — | — | CN | disclosed |