Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 9/20 | 0.48 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.47 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.47 |
| ▸ | MAP3K20 | Q9NYL2 | 1/20 | 0.47 |
| ▸ | MAP3K2 | Q9Y2U5 | 1/20 | 0.47 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.45 |
| ▸ | CASR | P41180 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.43 |
| ▸ | IDH1 | O75874 | 1/20 | 0.43 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2853347 | 0.84 | TRPV1 (0.41) | CCR1MAPK14ALDH1A1IDH1PSMD14 | |
| SCHEMBL2859298 | 0.82 | DDR1 (0.49) | CCR1DDR1MAPK11MAPK14DDR2 | |
| SCHEMBL2855580 | 0.81 | CCR1 (0.62) | CCR1DDR1MAPK11MAPK14DDR2 | |
| SCHEMBL2861147 | 0.81 | KDM4E (0.67) | CCR1DDR1MAPK11MAPK14DDR2 | |
| SCHEMBL2854820 | 0.80 | MAPK14 (0.47) | CCR1DDR1MAPK11MAPK14DDR2 | |
| SCHEMBL2850153 | 0.79 | KDM4E (0.63) | CCR1DDR1MAPK11MAPK14DDR2 | |
| SCHEMBL2850226 | 0.78 | MALT1 (0.56) | — | |
| SCHEMBL2850548 | 0.78 | CCR1 (0.61) | CCR1DDR1MAPK11MAPK14DDR2 | |
| SCHEMBL2295633 | 0.78 | MAPT (0.60) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2855376 | 0.78 | CCR1 (0.60) | CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |