Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.38 |
| ▸ | STAMBP | O95630 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2852635 | 0.87 | EPHX1 (0.44) | — | |
| SCHEMBL2850508 | 0.84 | CCR1 (0.48) | PSMD14STAMBPCCR1MAPK14IDH1 | |
| SCHEMBL2861682 | 0.84 | ALDH1A1 (0.48) | TRPV1ALDH1A1HPGD | |
| SCHEMBL2854795 | 0.84 | SMN1; SMN2 (0.44) | TRPV1FAAHMAPTMAPK14ALDH1A1 | |
| SCHEMBL2859504 | 0.84 | TAAR1 (0.43) | TRPV1CCR1MAPT | |
| SCHEMBL2853334 | 0.83 | CCR1 (0.47) | CCR1MAPTPTGER4ALDH1A1HPGD | |
| SCHEMBL2854467 | 0.83 | MAPT (0.36) | TRPV1MAPTPTGER4MAPK14ALDH1A1 | |
| SCHEMBL2852454 | 0.83 | KDM4E (0.48) | FAAHCCR1MAPTPTGER4MAPK14 | |
| SCHEMBL2857615 | 0.82 | MTOR (0.37) | TRPV1FAAHMAPTPTGER4MAPK14 | |
| SCHEMBL2860715 | 0.81 | ALDH1A1 (0.46) | CCR1MAPTMAPK14ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |