Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 15/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2856252 | 0.91 | P2RX1 (0.49) | CCR1 | |
| SCHEMBL2848180 | 0.87 | CCR1 (0.51) | CCR1LMNAHPGDMEN1KMT2A | |
| SCHEMBL2857181 | 0.85 | CCR1 (0.47) | CCR1LMNAHPGDMEN1PLA2G1B | |
| SCHEMBL2859933 | 0.83 | CCR1 (0.80) | CCR1LMNAHPGDMEN1PLA2G1B | |
| SCHEMBL2854432 | 0.83 | CCR1 (0.68) | CCR1LMNAHPGDMEN1PLA2G1B | |
| SCHEMBL2855742 | 0.83 | CCR1 (0.58) | CCR1LMNAHPGDMEN1PLA2G1B | |
| SCHEMBL2859642 | 0.82 | CCR1 (0.73) | CCR1HPGD | |
| SCHEMBL2860195 | 0.82 | CCR1 (0.70) | CCR1LMNAHPGD | |
| SCHEMBL2852810 | 0.82 | KDM4E (0.48) | HPGDGAA | |
| SCHEMBL2859008 | 0.81 | LMNA (0.66) | CCR1LMNAHPGDMEN1PLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |