Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 3/20 | 0.41 |
| ▸ | RHEB | Q15382 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 11/20 | 0.35 |
| ▸ | KIT | P10721 | 2/20 | 0.35 |
| ▸ | FLT3 | P36888 | 2/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28507679 | 0.99 | GRM1 (0.41) | GRM1RHEBFFAR4METKIT | |
| SCHEMBL28507659 | 0.85 | PIP4K2A (0.38) | GRM1FFAR4METROCK1 | |
| Hydrochloric Acid SCHEMBL28506157 | 0.85 | PIP4K2A (0.38) | GRM1FFAR4METROCK1 | |
| SCHEMBL28510258 | 0.83 | TYRO3 (0.36) | RHEBROCK1KDR | |
| SCHEMBL28516108 | 0.81 | APP (0.39) | GRM1RHEB | |
| SCHEMBL28515086 | 0.81 | LOXL2 (0.38) | RHEBMETROCK1 | |
| SCHEMBL18049205 | 0.80 | LOXL2 (0.47) | ROCK1 | |
| Hydrochloric Acid SCHEMBL28503674 | 0.80 | APP (0.38) | GRM1RHEB | |
| Hydrochloric Acid SCHEMBL28905577 | 0.80 | LOXL2 (0.37) | RHEBMETROCK1 | |
| Hydrochloric Acid SCHEMBL18049347 | 0.80 | LOXL2 (0.47) | ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107624110-B | Lysyl oxidase-like 2 inhibitors and uses thereof | 法玛克亚公司 | 2021-01-26 | — | — | CN | disclosed |