Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 6/20 | 0.36 |
| ▸ | RAB9A | P51151 | 6/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.33 |
| ▸ | LYN | P07948 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | RHEB | Q15382 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28503674 | 0.99 | APP (0.38) | APPNPC1RAB9ASMN1; SMN2PDE10A | |
| SCHEMBL18069327 | 0.84 | NPC1 (0.35) | NPC1RAB9ASMN1; SMN2PDE10ASLC2A1 | |
| SCHEMBL18049346 | 0.84 | LOXL2 (0.42) | NPC1RAB9ASMN1; SMN2PDE10AALDH1A1 | |
| SCHEMBL18049340 | 0.84 | USP30 (0.36) | NPC1RAB9ASMN1; SMN2PDE10ASLC2A1 | |
| Hydrochloric Acid SCHEMBL18049355 | 0.83 | LOXL2 (0.41) | NPC1RAB9ASMN1; SMN2PDE10AALDH1A1 | |
| SCHEMBL28505584 | 0.81 | GRM1 (0.41) | RHEBGRM1 | |
| Hydrochloric Acid SCHEMBL28507679 | 0.80 | GRM1 (0.41) | RHEBGRM1 | |
| SCHEMBL28505655 | 0.77 | NPC1 (0.39) | APPNPC1RAB9ASMN1; SMN2PDE10A | |
| SCHEMBL28510258 | 0.72 | TYRO3 (0.36) | RHEB | |
| SCHEMBL28507659 | 0.72 | PIP4K2A (0.38) | MAPTMEN1KMT2AGRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107624110-B | Lysyl oxidase-like 2 inhibitors and uses thereof | 法玛克亚公司 | 2021-01-26 | — | — | CN | disclosed |