Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYRO3 | Q06418 | 7/20 | 0.36 |
| ▸ | AXL | P30530 | 4/20 | 0.33 |
| ▸ | MERTK | Q12866 | 3/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | RHEB | Q15382 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 4/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28906716 | 0.86 | LOXL2 (0.35) | TYRO3SYKRHEBHTR3AROCK1 | |
| SCHEMBL28505584 | 0.83 | GRM1 (0.41) | RHEBROCK1KDR | |
| SCHEMBL18049133 | 0.83 | LOXL2 (0.44) | ROCK1LOXL2 | |
| Hydrochloric Acid SCHEMBL28507679 | 0.82 | GRM1 (0.41) | RHEBROCK1LOXL2KDR | |
| Hydrochloric Acid SCHEMBL18049171 | 0.82 | LOXL2 (0.44) | ROCK1LOXL2 | |
| SCHEMBL28507659 | 0.82 | PIP4K2A (0.38) | SYKROCK1 | |
| SCHEMBL28567884 | 0.82 | LOXL2 (0.39) | TYRO3AXLMERTKSYKRHEB | |
| Hydrochloric Acid SCHEMBL28574601 | 0.81 | LOXL2 (0.39) | TYRO3AXLMERTKSYKRHEB | |
| Hydrochloric Acid SCHEMBL28506157 | 0.81 | PIP4K2A (0.38) | SYKROCK1 | |
| SCHEMBL18361992 | 0.77 | LOXL2 (0.38) | TYRO3SYKRHEBHTR3ALOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107624110-B | Lysyl oxidase-like 2 inhibitors and uses thereof | 法玛克亚公司 | 2021-01-26 | — | — | CN | disclosed |