Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28905459 | 0.98 | MEN1 (0.52) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL22326177 | 0.96 | MEN1 (0.48) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL22326167 | 0.96 | MEN1 (0.48) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL22326195 | 0.96 | MEN1 (0.48) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL21647630 | 0.93 | TSHR (0.46) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL23777349 | 0.91 | MEN1 (0.48) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL28612804 | 0.89 | GAA (0.52) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL5246720 | 0.84 | LMNA (0.41) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL2636144 | 0.84 | ACHE (0.46) | GAATSHRLMNACHRM2CHRM4 | |
| SCHEMBL11752286 | 0.84 | ACHE (0.46) | GAATSHRLMNACHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112105385-A | IRAK degrading agents and uses thereof | 凯麦拉医疗公司 | 2020-12-18 | — | — | CN | disclosed |