Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5246720 | 0.91 | LMNA (0.41) | GAACYP4F2CYP4A11ACHELMNA | |
| SCHEMBL2636144 | 0.91 | ACHE (0.46) | GAACYP4F2CYP4A11ACHELMNA | |
| SCHEMBL22326322 | 0.91 | ACHE (0.46) | GAACYP4F2CYP4A11ACHELMNA | |
| SCHEMBL3423352 | 0.91 | ACHE (0.46) | GAACYP4F2CYP4A11ACHELMNA | |
| SCHEMBL11752286 | 0.91 | ACHE (0.46) | GAACYP4F2CYP4A11ACHELMNA | |
| SCHEMBL23152128 | 0.91 | ACHE (0.46) | GAACYP4F2CYP4A11ACHELMNA | |
| SCHEMBL28506271 | 0.89 | MEN1 (0.48) | GAACYP4F2CYP4A11ACHELMNA | |
| SCHEMBL1132887 | 0.89 | — | — | |
| SCHEMBL28905459 | 0.88 | MEN1 (0.52) | GAACYP4F2CYP4A11ACHELMNA | |
| SCHEMBL21647630 | 0.87 | TSHR (0.46) | GAACYP4F2CYP4A11ACHELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108136044-B | Imide-based proteolytic modulators and related methods of use | 阿尔维纳斯运营股份有限公司 | 2021-08-10 | — | — | CN | disclosed |