Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.39 |
| ▸ | DRD1 | P21728 | 5/20 | 0.39 |
| ▸ | DRD4 | P21917 | 5/20 | 0.39 |
| ▸ | DRD5 | P21918 | 5/20 | 0.39 |
| ▸ | DRD3 | P35462 | 5/20 | 0.39 |
| ▸ | MAOA | P21397 | 3/20 | 0.37 |
| ▸ | HTR6 | P50406 | 3/20 | 0.33 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28503558 | 0.81 | KCNH2 (0.47) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL21580816 | 0.76 | PDE3B (0.39) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL1888143 | 0.71 | KMT2A (0.53) | KDM4E | |
| SCHEMBL4265852 | 0.66 | NR1H2 (0.46) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL1428089 | 0.64 | HRH3 (0.41) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL3654090 | 0.63 | DRD2 (0.52) | DRD2DRD3HRH3 | |
| SCHEMBL28450181 | 0.62 | SMN1; SMN2 (0.57) | HRH3KDM4E | |
| SCHEMBL6139524 | 0.62 | LMNA (0.58) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL1427424 | 0.62 | POLB (0.44) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL576035 | 0.61 | CA2 (0.50) | DRD2DRD1DRD4DRD5DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112204037-A | Novel oxoquinolizine compounds for the treatment and prevention of bacterial infections | 豪夫迈·罗氏有限公司 | 2021-01-08 | — | — | CN | disclosed |