Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 8/20 | 0.41 |
| ▸ | MAN2B1 | O00754 | 1/20 | 0.39 |
| ▸ | NPC1L1 | Q9UHC9 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28507292 | 1.00 | MAOA (0.43) | MAOAMAOBTDP1EPHX1DRD2 | |
| SCHEMBL28520872 | 0.96 | EPHX1 (0.43) | MAOAMAOBTDP1EPHX1DRD2 | |
| SCHEMBL28520869 | 0.96 | EPHX1 (0.43) | MAOAMAOBTDP1EPHX1DRD2 | |
| SCHEMBL28938875 | 0.84 | EPHX1 (0.42) | TDP1EPHX1DRD2MAN2B1NPC1L1 | |
| SCHEMBL19965191 | 0.82 | F2 (0.46) | MAOAMAOBTDP1EPHX1DRD2 | |
| SCHEMBL21066904 | 0.80 | TDP1 (0.42) | TDP1EPHX1DRD2MAN2B1CHRM2 | |
| SCHEMBL21066903 | 0.80 | TDP1 (0.42) | TDP1EPHX1DRD2MAN2B1CHRM2 | |
| SCHEMBL23005327 | 0.79 | CHRM2 (0.41) | MAOAMAOBTDP1EPHX1DRD2 | |
| SCHEMBL23005328 | 0.79 | CHRM2 (0.41) | MAOAMAOBTDP1EPHX1DRD2 | |
| SCHEMBL29004598 | 0.78 | CTSK (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110139644-B | Compositions and methods for treating insulin resistance | 坦普尔大学 | 2023-05-23 | — | — | CN | disclosed |
| CN-112088006-A | Compositions and methods for treating insulin resistance | 坦普尔大学 | 2020-12-15 | — | — | CN | disclosed |