Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 9/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | BACE1 | P56817 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NPC1L1 | Q9UHC9 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28520872 | 1.00 | EPHX1 (0.43) | EPHX1DRD2MAOAMAOBACHE | |
| SCHEMBL28507288 | 0.96 | MAOA (0.43) | EPHX1DRD2MAOAMAOBACHE | |
| SCHEMBL28507292 | 0.96 | MAOA (0.43) | EPHX1DRD2MAOAMAOBACHE | |
| SCHEMBL28938875 | 0.88 | EPHX1 (0.42) | EPHX1DRD2ACHEBACE1CNR2 | |
| SCHEMBL28938876 | 0.81 | F2 (0.48) | EPHX1DRD2ACHEBACE1CNR2 | |
| SCHEMBL19965194 | 0.81 | F2 (0.48) | EPHX1DRD2ACHEBACE1CNR2 | |
| SCHEMBL29004599 | 0.80 | CTSK (0.35) | F2F10PRSS1 | |
| SCHEMBL29004598 | 0.80 | CTSK (0.35) | F2F10PRSS1 | |
| SCHEMBL23005330 | 0.80 | EPHX1 (0.44) | EPHX1DRD2ACHEBACE1CNR2 | |
| SCHEMBL23005331 | 0.80 | EPHX1 (0.44) | EPHX1DRD2ACHEBACE1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110139644-B | Compositions and methods for treating insulin resistance | 坦普尔大学 | 2023-05-23 | — | — | CN | disclosed |
| CN-115461049-A | (S) -2-amino-6- ((3-aminopropyl) amino) hexanoic Acid (APL) for the treatment of non-alcoholic steatohepatitis (NASH), liver inflammation, hepatocellular ballooning, liver fibrosis and steatosis | 坦普尔大学 | 2022-12-09 | — | — | CN | disclosed |
| CN-112088006-A | Compositions and methods for treating insulin resistance | 坦普尔大学 | 2020-12-15 | — | — | CN | disclosed |