Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PLA2G6 | O60733 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1763199 | 0.87 | KDM1A (0.50) | KDM1ASLC6A4DRD2MTNR1AIDO1 | |
| SCHEMBL1763476 | 0.87 | KDM1A (0.50) | KDM1ASLC6A4DRD2MTNR1AIDO1 | |
| SCHEMBL28499008 | 0.77 | HTR2C (0.47) | KDM1AALDH1A1NPSR1 | |
| SCHEMBL31444323 | 0.75 | SMN1; SMN2 (0.39) | KDM1APOLBMAPTSMN1; SMN2TP53 | |
| SCHEMBL31369542 | 0.74 | CYP2C9 (0.45) | KDM1AMTNR1AIDO1MTNR1BPLA2G6 | |
| SCHEMBL13811323 | 0.74 | KDM1A (0.52) | KDM1ASLC6A4DRD2MTNR1AIDO1 | |
| SCHEMBL22721096 | 0.73 | KCNH2 (0.35) | SLC6A3 | |
| SCHEMBL28946638 | 0.72 | GABRA1 (0.34) | SLC6A4SLC6A2FAAHALDH1A1LMNA | |
| SCHEMBL31172516 | 0.72 | KDM1A (0.66) | KDM1ASLC6A4DRD2MTNR1AIDO1 | |
| SCHEMBL10800761 | 0.72 | MTNR1A (0.50) | KDM1ASLC6A4DRD2MTNR1AIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112010859-B | Fused ring compound, preparation method and application thereof | 中国科学院上海药物研究所 | 2022-07-19 | — | — | CN | disclosed |
| CN-112010859-A | Fused ring compound, preparation method and application thereof | 中国科学院上海药物研究所 | 2020-12-01 | — | — | CN | disclosed |