Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1763476 | 1.00 | KDM1A (0.50) | KDM1AMTNR1AIDO1SLC6A4SLC6A2 | |
| SCHEMBL28508192 | 0.87 | KDM1A (0.43) | KDM1AMTNR1AIDO1SLC6A4SLC6A2 | |
| SCHEMBL31369542 | 0.82 | CYP2C9 (0.45) | KDM1AMTNR1AIDO1MTNR1BPLA2G6 | |
| SCHEMBL13811323 | 0.81 | KDM1A (0.52) | KDM1AMTNR1AIDO1SLC6A4SLC6A2 | |
| SCHEMBL2724251 | 0.79 | GRIN2D (0.48) | SLC6A3 | |
| SCHEMBL5095438 | 0.79 | GRIN2D (0.48) | SLC6A3 | |
| SCHEMBL29468003 | 0.79 | GRIN2D (0.48) | SLC6A3 | |
| SCHEMBL10800761 | 0.79 | MTNR1A (0.50) | KDM1AMTNR1AIDO1SLC6A4SLC6A2 | |
| SCHEMBL7705258 | 0.77 | KDM1A (0.44) | KDM1AMTNR1AIDO1SLC6A4SLC6A2 | |
| SCHEMBL4149119 | 0.77 | SCN9A (0.46) | KDM1AMTNR1AIDO1SLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8759541-B2 | Chiral acyclic diaminocarbene ligands, precursors therefore and their use in organic synthesis reactions | THADANI AVINASH N (CA) | 2014-06-24 | — | — | US | disclosed |
| US-20110118475-A1 | CHIRAL ACYCLIC DIAMINOCARBENE LIGANDS, PRECURSORS THEREFORE AND THEIR USE IN ORGANIC SYNTHESIS REACTIONS | THADANI AVINASH N | 2011-05-19 | — | — | US | disclosed |
| WO-2010003226-A1 | CHIRAL ACYCLIC DIAMINOCARBENE LIGANDS, PRECURSORS THEREFORE AND THEIR USE IN ORGANIC SYNTHESIS REACTIONS | THADANI AVINASH N (CA) | 2010-01-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110118475-A1 | CHIRAL ACYCLIC DIAMINOCARBENE LIGANDS, PRECURSORS THEREFORE AND THEIR USE IN ORGANIC SYNTHESIS REACTIONS | AOC1, ODC1, AMD1 | KDM1A 3656/4885MTNR1A 2992/4885IDO1 1747/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.