Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.51 |
| ▸ | PTPRC | P08575 | 1/20 | 0.51 |
| ▸ | PTPRF | P10586 | 1/20 | 0.51 |
| ▸ | CDC25B | P30305 | 1/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | RET | P07949 | 1/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.47 |
| ▸ | LTK | P29376 | 1/20 | 0.47 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.47 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28503567 | 0.82 | PTPN1 (0.46) | PTPN1PTPRCPTPRFCDC25BMEN1 | |
| SCHEMBL28336963 | 0.82 | PTPN1 (0.46) | PTPN1PTPRCPTPRFCDC25BMEN1 | |
| SCHEMBL28514484 | 0.81 | PTPN1 (0.55) | PTPN1PTPRCPTPRFCDC25BKDR | |
| SCHEMBL28506037 | 0.81 | PTPN1 (0.55) | PTPN1PTPRCPTPRFCDC25BMEN1 | |
| SCHEMBL9572016 | 0.80 | PTPN1 (0.77) | PTPN1PTPRCPTPRFCDC25BMEN1 | |
| SCHEMBL28516065 | 0.78 | PTPN1 (0.51) | PTPN1PTPRCPTPRFCDC25BHTR6 | |
| SCHEMBL5432612 | 0.76 | GPR84 (0.66) | PDE4BMEN1KMT2AMAPTGPR84 | |
| SCHEMBL5879148 | 0.75 | KDR (0.57) | PDE4BKDRMEN1KMT2ANTRK1 | |
| SCHEMBL7815879 | 0.74 | CDK4 (0.73) | KDRPRKD3ABL1PDGFRBFLT3 | |
| SCHEMBL7816070 | 0.74 | CDK4 (0.78) | PDE4BKDRMEN1KMT2ANTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110437124-B | Preparation method of indoloquinone derivative | 中国科学院成都有机化学有限公司 | 2020-12-22 | — | — | CN | disclosed |