Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.55 |
| ▸ | PTPRC | P08575 | 3/20 | 0.55 |
| ▸ | PTPRF | P10586 | 1/20 | 0.55 |
| ▸ | CDC25B | P30305 | 1/20 | 0.55 |
| ▸ | CAMK2D | Q13557 | 3/20 | 0.46 |
| ▸ | BACE1 | P56817 | 2/20 | 0.46 |
| ▸ | S100A4 | P26447 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
| ▸ | IGF1R | P08069 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | FLT4 | P35916 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | TEK | Q02763 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 2/20 | 0.41 |
| ▸ | CLK1 | P49759 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28506037 | 0.84 | PTPN1 (0.55) | PTPN1PTPRCPTPRFCDC25BBACE1 | |
| SCHEMBL9572016 | 0.83 | PTPN1 (0.77) | PTPN1PTPRCPTPRFCDC25BCAMK2D | |
| SCHEMBL28516065 | 0.81 | PTPN1 (0.51) | PTPN1PTPRCPTPRFCDC25BCAMK2D | |
| SCHEMBL28508263 | 0.81 | PTPN1 (0.51) | PTPN1PTPRCPTPRFCDC25BPDGFRB | |
| SCHEMBL7737770 | 0.76 | PDGFRB (0.44) | PTPN1CAMK2DEGFRERBB2IGF1R | |
| SCHEMBL28906711 | 0.76 | PTPN1 (0.55) | PTPN1PTPRCPTPRFCDC25BBACE1 | |
| SCHEMBL28503581 | 0.76 | PTPN1 (0.55) | PTPN1PTPRCPTPRFCDC25BBACE1 | |
| SCHEMBL28336963 | 0.75 | PTPN1 (0.46) | PTPN1PTPRCPTPRFCDC25BBACE1 | |
| SCHEMBL28503567 | 0.75 | PTPN1 (0.46) | PTPN1PTPRCPTPRFCDC25BBACE1 | |
| SCHEMBL20846072 | 0.74 | GPR84 (0.47) | CAMK2DGPR84PIM1CLK1CDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110437124-B | Preparation method of indoloquinone derivative | 中国科学院成都有机化学有限公司 | 2020-12-22 | — | — | CN | disclosed |