Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.46 |
| ▸ | PTPRC | P08575 | 1/20 | 0.45 |
| ▸ | PTPRF | P10586 | 1/20 | 0.45 |
| ▸ | CDC25B | P30305 | 1/20 | 0.45 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 3/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA4 | P22748 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28336963 | 0.83 | PTPN1 (0.46) | PTPN1PTPRCPTPRFCDC25BBACE1 | |
| SCHEMBL28508263 | 0.82 | PTPN1 (0.51) | PTPN1PTPRCPTPRFCDC25BMAOA | |
| SCHEMBL28506037 | 0.75 | PTPN1 (0.55) | PTPN1PTPRCPTPRFCDC25BBACE1 | |
| SCHEMBL28514484 | 0.75 | PTPN1 (0.55) | PTPN1PTPRCPTPRFCDC25BBACE1 | |
| SCHEMBL28516065 | 0.75 | PTPN1 (0.51) | PTPN1PTPRCPTPRFCDC25BBACE1 | |
| SCHEMBL9572016 | 0.74 | PTPN1 (0.77) | PTPN1PTPRCPTPRFCDC25BBACE1 | |
| SCHEMBL28738017 | 0.69 | MTNR1A (0.41) | GSTP1MAOBCA12CA4CA9 | |
| SCHEMBL28503581 | 0.68 | PTPN1 (0.55) | PTPN1PTPRCPTPRFCDC25BBACE1 | |
| SCHEMBL28906711 | 0.68 | PTPN1 (0.55) | PTPN1PTPRCPTPRFCDC25BBACE1 | |
| SCHEMBL25057108 | 0.65 | HTR1A (0.72) | MEN1KMT2AKDM4ETSHRHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110437124-B | Preparation method of indoloquinone derivative | 中国科学院成都有机化学有限公司 | 2020-12-22 | — | — | CN | disclosed |