Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 6/20 | 0.40 |
| ▸ | PPARD | Q03181 | 6/20 | 0.40 |
| ▸ | PPARA | Q07869 | 6/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.40 |
| ▸ | TLR2 | O60603 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | FABP4 | P15090 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10699569 | 0.92 | LMNA (0.41) | TSHRLMNANFKB1PMP22ALDH1A1 | |
| SCHEMBL26907179 | 0.85 | EGLN1 (0.41) | TSHRLMNANFKB1PMP22SLC22A6 | |
| SCHEMBL28165411 | 0.85 | TSHR (0.46) | TSHRLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL27482958 | 0.82 | DGKA (0.52) | TSHRLMNAGPR84FFAR1FFAR4 | |
| SCHEMBL27700699 | 0.82 | DGKA (0.52) | TSHRLMNAGPR84FFAR1FFAR4 | |
| SCHEMBL28360017 | 0.82 | DGKA (0.52) | TSHRLMNAGPR84FFAR1FFAR4 | |
| SCHEMBL29169676 | 0.82 | DGKA (0.52) | TSHRLMNAGPR84FFAR1FFAR4 | |
| SCHEMBL29199661 | 0.82 | DGKA (0.52) | TSHRLMNAGPR84FFAR1FFAR4 | |
| Hydrochloric Acid SCHEMBL28914870 | 0.81 | CNR2 (0.50) | TSHRLMNAGPR84ALDH1A1MAPT | |
| SCHEMBL27358889 | 0.80 | ALDH1A1 (0.40) | TSHRLMNAALDH1A1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118355020-A | Therapeutic compounds for HIV virus infection | 吉利德科学公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-118324767-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-07-12 | — | — | CN | disclosed |
| CN-114555123-B | Combination therapy for the treatment of myelodysplastic syndrome and acute myeloid leukemia | 四十七公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-117736207-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-03-22 | — | — | CN | disclosed |
| CN-115362003-B | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-03-22 | — | — | CN | disclosed |
| CN-117480155-A | Diacylglycerol kinase modulating compounds | 吉利德科学公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-117396478-A | Diacylglycerol kinase modulating compounds | 吉利德科学公司 | 2024-01-12 | — | — | CN | disclosed |
| CN-117377671-A | Diacylglycerol kinase modulating compounds | 吉利德科学公司 | 2024-01-09 | — | — | CN | disclosed |
| CN-117355531-A | Diacylglycerol kinase modulating compounds | 吉利德科学公司 | 2024-01-05 | — | — | CN | disclosed |
| CN-117120474-A | Co-inhibition of CD 47/SIRPalpha binding and NEDD8 activating enzyme E1 regulatory subunit for the treatment of cancer | 吉利德科学公司 | 2023-11-24 | — | — | CN | disclosed |
| CN-116529258-A | Interleukin-2-Fc fusion proteins and methods of use | 吉利德科学公司 | 2023-08-01 | — | — | CN | disclosed |
| CN-116437958-A | Method for identifying HIV patients susceptible to therapy with gp120 CD4 binding site directed antibodies | 吉利德科学公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-112218651-A | Immunopotentiating RNA for combination with chimeric antigen receptor therapy | 诺华公司 | 2021-01-12 | — | — | CN | disclosed |