Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | WDR5 | P61964 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | MAP2 | P11137 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29395135 | 0.81 | POLB (0.46) | MAPTGAANPSR1KDM4EMEN1 | |
| SCHEMBL28509508 | 0.81 | POLB (0.46) | MAPTGAANPSR1KDM4EMEN1 | |
| SCHEMBL28961629 | 0.76 | FDPS (0.42) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL31425731 | 0.74 | ALDH1A1 (0.47) | MAPTGAAKDM4EMEN1KMT2A | |
| SCHEMBL31425730 | 0.72 | MAP2 (0.45) | GAAPTGS2MAP2 | |
| SCHEMBL28981318 | 0.71 | MAP2 (0.50) | MAPTNPSR1KDM4EMEN1KMT2A | |
| SCHEMBL28981320 | 0.71 | ALDH1A1 (0.45) | MAPTGAANPSR1KDM4EMEN1 | |
| Methacrylic Acid SCHEMBL17206137 | 0.67 | HPRT1 (0.56) | MAPTKDM4EMEN1KMT2ATDP1 | |
| Phenanthrene SCHEMBL27623638 | 0.67 | ALDH1A1 (0.53) | MAPTGAAKDM4EMEN1KMT2A | |
| Phenanthrene SCHEMBL670439 | 0.67 | ALDH1A1 (0.53) | MAPTGAAKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114105981-A | Method for preparing benzimidazole [2,1-a ] isoquinoline-6 (5H) -ketone compound | 怀化学院 | 2022-03-01 | — | — | CN | disclosed |