Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 7/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | VDR | P11473 | 1/20 | 0.39 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29199906 | 0.80 | KMT2A (0.59) | HTTALDH1A1GAAHPGDKMT2A | |
| SCHEMBL30827911 | 0.80 | KMT2A (0.59) | HTTALDH1A1GAAHPGDKMT2A | |
| SCHEMBL28501477 | 0.78 | CRHBP (0.50) | HTTALDH1A1GAAHPGDCRHBP | |
| SCHEMBL28500108 | 0.76 | ALDH1A1 (0.50) | HTTALDH1A1GAAHPGDCRHBP | |
| SCHEMBL23202844 | 0.75 | CCNC (0.44) | HTTALDH1A1GAAHPGDKMT2A | |
| SCHEMBL30827862 | 0.75 | CCNC (0.44) | HTTALDH1A1GAAHPGDKMT2A | |
| SCHEMBL27950617 | 0.74 | ALDH1A1 (0.49) | HTTALDH1A1GAAHPGDCRHBP | |
| SCHEMBL28506922 | 0.72 | ALDH1A1 (0.55) | HTTALDH1A1GAAHPGDCRHBP | |
| SCHEMBL28511396 | 0.71 | KMT2A (0.67) | HTTALDH1A1GAACRHBPCRHR2 | |
| SCHEMBL28501475 | 0.71 | CRHBP (0.50) | HTTALDH1A1GAAHPGDCRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112204010-B | Heterocyclic derivatives and uses thereof | C&C新药研究所 | 2024-03-19 | — | — | CN | disclosed |
| CN-112204010-A | Heterocyclic derivatives and use thereof | C&C新药研究所 | 2021-01-08 | — | — | CN | disclosed |