Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 4/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.59 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 3/20 | 0.55 |
| ▸ | DRD3 | P35462 | 3/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | HTR7 | P34969 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28906765 | 0.85 | ATF4 (0.61) | KCNH2CACNA1GHTR7TSHR | |
| SCHEMBL20854558 | 0.83 | KCNH2 (0.67) | DRD4KCNH2CACNA1GLMNAMAPK1 | |
| SCHEMBL11365346 | 0.81 | KCNH2 (0.86) | DRD4KCNH2CACNA1GLMNAMAPK1 | |
| SCHEMBL5709502 | 0.81 | SIGMAR1 (0.60) | KMT2AMEN1DRD2DRD3 | |
| SCHEMBL11370338 | 0.81 | KCNH2 (0.68) | KCNH2CACNA1GLMNAMAPK1KMT2A | |
| SCHEMBL28619817 | 0.80 | SIGMAR1 (0.62) | KMT2AMEN1DRD2DRD3 | |
| SCHEMBL21062177 | 0.79 | DRD4 (0.62) | DRD4KCNH2CACNA1GLMNAMAPK1 | |
| SCHEMBL21050207 | 0.79 | DRD4 (0.62) | DRD4KCNH2CACNA1GLMNAMAPK1 | |
| SCHEMBL28664562 | 0.79 | ATF4 (0.56) | KCNH2CACNA1GHTR7TSHR | |
| Trifluoroacetic Acid SCHEMBL21050185 | 0.79 | DRD4 (0.59) | DRD4KCNH2CACNA1GLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111757739-A | Integrated stress pathway inhibitors | 普拉西斯生物技术有限责任公司 | 2020-10-09 | — | — | CN | disclosed |