Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 9/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | MYC | P01106 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | CA4 | P22748 | 3/20 | 0.34 |
| ▸ | CA9 | Q16790 | 3/20 | 0.34 |
| ▸ | REN | P00797 | 1/20 | 0.33 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2849210 | 0.82 | MYC (0.45) | DRD2MYCHTR6BIRC2 | |
| Water SCHEMBL5996484 | 0.81 | MYC (0.44) | DRD2MYCHTR6BIRC2 | |
| SCHEMBL6849293 | 0.78 | HTR6 (0.43) | ADRB1DRD2MYCHTR6 | |
| SCHEMBL6288232 | 0.78 | HTR6 (0.43) | ADRB1DRD2MYCHTR6CA2 | |
| SCHEMBL6847420 | 0.78 | HDAC1 (0.41) | ADRB1DRD2MYCHTR6 | |
| SCHEMBL6849062 | 0.76 | RPS6KB1 (0.47) | MYCHTR6 | |
| SCHEMBL6848056 | 0.75 | LATS1 (0.40) | ADRB1DRD2MYCHTR6 | |
| SCHEMBL11846933 | 0.74 | HTR1A (0.42) | ADRB1DRD2REN | |
| SCHEMBL6847591 | 0.73 | HTR6 (0.39) | MYCHTR6 | |
| SCHEMBL8632814 | 0.72 | HTR6 (0.67) | ADRB1DRD2MYCHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7652017-B2 | Remedies and/or preventives for nervous system disorders | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2010-01-26 | — | — | US | claimed |
| EP-1374868-A1 | REMEDIES AND/OR PREVENTIVES FOR DIABETIC ISCHEMIC HEART DISEASES | Mitsubishi Pharma Corporation (JP) | 2004-01-02 | — | — | EP | claimed |
| EP-1374868-A1 | REMEDIES AND/OR PREVENTIVES FOR DIABETIC ISCHEMIC HEART DISEASES | Mitsubishi Pharma Corporation (JP) | 2004-01-02 | — | — | EP | disclosed |