Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 11/20 | 0.45 |
| ▸ | RCOR1 | Q9UKL0 | 7/20 | 0.45 |
| ▸ | LIG1 | P18858 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4133969 | 0.91 | KDM1A (0.44) | KDM1ARCOR1LIG1MAOBKCNH2 | |
| SCHEMBL900614 | 0.81 | KDM1A (0.45) | KDM1ARCOR1LIG1MAOBKCNH2 | |
| SCHEMBL28519822 | 0.81 | ALDH1A1 (0.40) | MAOBMEN1KMT2ALMNAMAOA | |
| SCHEMBL28521164 | 0.81 | KDM1A (0.45) | KDM1ARCOR1LIG1MAOBKMT2A | |
| SCHEMBL307974 | 0.81 | KDM1A (0.48) | KDM1AMAOBMAOA | |
| SCHEMBL28524795 | 0.81 | KDM1A (0.51) | KDM1ARCOR1MEN1KMT2AHTR2C | |
| Water SCHEMBL2458176 | 0.80 | KDM1A (0.44) | KDM1ARCOR1LIG1MAOBKCNH2 | |
| Hydrochloric Acid SCHEMBL29430083 | 0.80 | KDM1A (0.47) | KDM1ARCOR1LIG1MAOBKCNH2 | |
| SCHEMBL28524760 | 0.77 | RAB9A (0.48) | KDM1AMAOBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL28885346 | 0.77 | KDM1A (0.41) | KDM1ARCOR1LIG1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112142619-B | 1, 1-cyclopropane dicarboxylic acid amide compound and preparation method and application thereof | 浙江工业大学 | 2023-01-10 | — | — | CN | disclosed |
| CN-112142619-A | 1, 1-cyclopropane dicarboxylic acid amide compound and preparation method and application thereof | 浙江工业大学 | 2020-12-29 | — | — | CN | disclosed |