Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.41 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.41 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.41 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.41 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12119025 | 0.81 | CYP4A11 (0.40) | NR1H4MEN1KMT2AABCC9ABCC8 | |
| SCHEMBL17506449 | 0.80 | CYP1A2 (0.56) | MEN1KMT2AABCC9ABCC8KCNJ11 | |
| SCHEMBL17666342 | 0.79 | MEN1 (0.61) | MEN1KMT2APDK1PDK2PDK3 | |
| SCHEMBL13322082 | 0.78 | HPGD (0.53) | NR1H4MEN1KMT2AGPR174CYP1A2 | |
| SCHEMBL15058961 | 0.78 | ALDH1A1 (0.50) | MEN1KMT2AABCC9ABCC8KCNJ11 | |
| SCHEMBL1310816 | 0.76 | ABCC9 (0.44) | MEN1KMT2AABCC9ABCC8KCNJ11 | |
| SCHEMBL746589 | 0.76 | MAPT (0.52) | MEN1KMT2AABCC9ABCC8KCNJ11 | |
| SCHEMBL16983107 | 0.76 | MAPK1 (0.55) | MEN1KMT2APDK1PDK2PDK3 | |
| SCHEMBL913000 | 0.75 | ABCC9 (0.52) | MEN1KMT2AABCC9ABCC8KCNJ11 | |
| SCHEMBL27447799 | 0.75 | ABCC9 (0.56) | NR1H4MEN1KMT2AABCC9ABCC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100130515-A1 | Polymorphs and solvates of a pharmaceutical and method of making | BIOGEN IDEC INC. (US) | 2010-05-27 | — | — | US | disclosed |
| US-20100130515-A1 | Polymorphs and solvates of a pharmaceutical and method of making | BIOGEN IDEC INC. (US) | 2010-05-27 | — | — | US | disclosed |
| EP-2117308-A1 | POLYMORPHS AND SOLVATES OF A PHARMACEUTICAL AND METHODS OF MAKING | Biogen Idec MA Inc. (US) | 2009-11-18 | — | — | EP | disclosed |
| WO-2008086201-A1 | POLYMORPHS AND SOLVATES OF A PHARMACEUTICAL AND METHODS OF MAKING | BIOGEN IDEC MA INC. (US) | 2008-07-17 | — | — | WO | disclosed |
| WO-2008086201-A1 | POLYMORPHS AND SOLVATES OF A PHARMACEUTICAL AND METHODS OF MAKING | BIOGEN IDEC MA INC. (US) | 2008-07-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130515-A1 | Polymorphs and solvates of a pharmaceutical and method of making | CYP3A7, CYP2D6, CYP3A5 | NR1H4 1685/4885MEN1 1598/4885KMT2A 3270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.