2-Methoxyethanol

2-Methoxyethanol

SCHEMBL28511657

COCCO.O=COc1ccc([N+](=O)[O-])cc1

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.44
LMNA P02545 3/20 0.44
CYP3A4 P08684 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
TP53 P04637 1/20 0.44
THRB P10828 1/20 0.44
MAPK1 P28482 1/20 0.44
HSD17B10 Q99714 1/20 0.44
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44
CES2 O00748 1/20 0.44
CES1 P23141 1/20 0.44
PTGS2 P35354 2/20 0.43
TSHR P16473 1/20 0.42
BCL9 O00512 1/20 0.42
CTNNB1 P35222 1/20 0.42
BCHE P06276 1/20 0.42
ACHE P22303 1/20 0.42
MEN1 O00255 1/20 0.42
CYP1A2 P05177 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL28356619 0.88 TSHR (0.50) ALDH1A1MAPK1CA1CA2CES2
SCHEMBL8433 0.82 HSPB1 (0.52) ALDH1A1LMNACYP3A4SMN1; SMN2TP53
SCHEMBL28135398 0.81 HSPB1 (0.50) ALDH1A1LMNACYP3A4SMN1; SMN2TP53
Ammonia Solution, Strong SCHEMBL27663814 0.81 HSPB1 (0.50) ALDH1A1LMNACYP3A4SMN1; SMN2TP53
Hydrochloric Acid SCHEMBL27912110 0.81 HSPB1 (0.50) ALDH1A1LMNACYP3A4SMN1; SMN2TP53
Hydrazine SCHEMBL27959578 0.77 CA1 (0.50) ALDH1A1LMNACYP3A4SMN1; SMN2TP53
SCHEMBL28285987 0.77 LMNA (0.47) ALDH1A1LMNACYP3A4SMN1; SMN2TP53
2-Methoxyethanol SCHEMBL29186967 0.75 POLB (0.49) ALDH1A1SMN1; SMN2MAPK1TSHRMEN1
SCHEMBL56460 0.74 MAPT (0.58) ALDH1A1LMNAPTGS2TSHRMAPT
SCHEMBL11583343 0.73 TSHR (0.49) MAPK1CA1CA2CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112245408-A Light-controlled release antibacterial peptide nanoparticle and preparation method and application thereof 华南理工大学 2021-01-22 CN disclosed
CN-112245408-A Light-controlled release antibacterial peptide nanoparticle and preparation method and application thereof 华南理工大学 2021-01-22 CN disclosed
CN-112023044-A Near-infrared light and pH dual-response oleic acid derivative nano drug-loaded material and preparation method and application thereof 华南理工大学 2020-12-04 CN disclosed