SCHEMBL28511792

SCHEMBL28511792

CCC(ON1C(=O)CCC1=O)C(=O)O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.37
KMT2A Q03164 1/20 0.35
ATM Q13315 1/20 0.35
LMNA P02545 1/20 0.34
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA3 P07451 1/20 0.34
CA4 P22748 1/20 0.34
CA6 P23280 1/20 0.34
CA5A P35218 1/20 0.34
CA7 P43166 1/20 0.34
CA9 Q16790 1/20 0.34
CA13 Q8N1Q1 1/20 0.34
CA14 Q9ULX7 1/20 0.34
CA5B Q9Y2D0 1/20 0.34
ALDH1A1 P00352 1/20 0.33
PKM P14618 1/20 0.33
PPARA Q07869 2/20 0.31
ALOX12 P18054 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19446211 0.75 TSHR (0.37) KMT2AATMLMNACA12CA1
SCHEMBL379296 0.74 PARL (0.34) KMT2AATMCA12CA1CA9
SCHEMBL230241 0.74 PARL (0.34) KMT2AATMCA12CA1CA9
SCHEMBL12140985 0.74 LMNA (0.32) LMNACA12CA1CA2CA3
SCHEMBL29355696 0.73 ALDH1A1 (0.46) KMT2ALMNACA12CA9ALDH1A1
SCHEMBL23468389 0.72 CHRM2 (0.33) LMNACA12CA1CA2CA3
SCHEMBL30439937 0.72
SCHEMBL327689 0.71 KMT2A (0.33) KMT2AATMLMNACA12CA1
SCHEMBL1140513 0.71 ALDH1A1 (0.33) KMT2AATMALDH1A1PKMPARL
SCHEMBL9150133 0.71 ALDH1A1 (0.33) KMT2AATMALDH1A1PKMPARL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112399859-A Selective TREG stimulator RUR20kD-IL-2 and related compositions 尼克塔治疗公司 2021-02-23 CN disclosed