Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28511192 | 0.86 | KMT2A (0.51) | RAPGEF4ALDH1A1MAPTHPGDPOLB | |
| SCHEMBL28502157 | 0.80 | GAA (0.52) | ALDH1A1MAPTPOLBL3MBTL1KDM4E | |
| SCHEMBL2236507 | 0.79 | ALDH1A1 (0.50) | RAPGEF4ALDH1A1MAPTHPGDPOLB | |
| SCHEMBL28504347 | 0.75 | KMT2A (0.54) | ALDH1A1MAPTPOLBKMT2AL3MBTL1 | |
| SCHEMBL28504346 | 0.75 | KMT2A (0.47) | ALDH1A1MAPTHPGDKMT2AL3MBTL1 | |
| SCHEMBL11193800 | 0.74 | ALDH1A1 (0.51) | RAPGEF4ALDH1A1MAPTHPGDPOLB | |
| SCHEMBL9683136 | 0.74 | KMT2A (0.49) | RAPGEF4ALDH1A1MAPTHPGDPOLB | |
| SCHEMBL11590652 | 0.74 | HTR6 (0.52) | RAPGEF4ALDH1A1MAPTPOLBKMT2A | |
| SCHEMBL28506091 | 0.74 | CD44 (0.48) | RAPGEF4ALDH1A1HPGDPOLBKMT2A | |
| SCHEMBL2487383 | 0.73 | ALDH1A1 (0.54) | RAPGEF4ALDH1A1MAPTHPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109096156-B | Disulfonyl meta-aryl diamine urease inhibitor and preparation method and application thereof | 吉首大学 | 2021-01-15 | — | — | CN | disclosed |