Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | RAPGEF4 | Q8WZA2 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11193800 | 0.87 | ALDH1A1 (0.51) | KMT2AALDH1A1HPGDMAPTPOLB | |
| SCHEMBL1538438 | 0.84 | KMT2A (0.56) | KMT2AGAAALDH1A1MAPTKDM4E | |
| SCHEMBL2236507 | 0.84 | ALDH1A1 (0.50) | KMT2AGAAALDH1A1HPGDMAPT | |
| SCHEMBL4400072 | 0.83 | GAA (0.49) | KMT2AGAAALDH1A1HPGDMAPT | |
| SCHEMBL9634830 | 0.83 | KMT2A (0.51) | KMT2AGAAALDH1A1HPGDMAPT | |
| SCHEMBL11225428 | 0.78 | HTR6 (0.47) | KMT2AALDH1A1HPGDMAPTPOLB | |
| SCHEMBL9634824 | 0.78 | GAA (0.56) | KMT2AGAAALDH1A1MAPTRAPGEF4 | |
| SCHEMBL16268967 | 0.77 | CNR2 (0.51) | KMT2AGAAALDH1A1HPGDMAPT | |
| SCHEMBL16268900 | 0.77 | HSD11B1 (0.47) | GAAALDH1A1HPGDMAPTPOLB | |
| Biphenyl SCHEMBL11199366 | 0.76 | KMT2A (0.49) | KMT2AGAAALDH1A1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091564-A | Catalytic oxidation of tetramethyldiphenyl sulfone | NEW JAPAN CHEMICAL CO., LTD. (JP) | 1992-02-25 | — | — | US | disclosed |