Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.47 |
| ▸ | AKR1B10 | O60218 | 8/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 8/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.40 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28516049 | 1.00 | ALOX5 (0.47) | ALOX5AKR1B10AKR1B1APPALDH1A1 | |
| SCHEMBL28512013 | 0.84 | LMNA (0.56) | ALOX5AKR1B10AKR1B1ALDH1A1HCAR2 | |
| SCHEMBL28512015 | 0.84 | LMNA (0.56) | ALOX5AKR1B10AKR1B1ALDH1A1HCAR2 | |
| SCHEMBL28521897 | 0.83 | PTGER3 (0.45) | ALOX5ALDH1A1KDM4ETP53MAPT | |
| SCHEMBL28521896 | 0.83 | PTGER3 (0.45) | ALOX5ALDH1A1KDM4ETP53MAPT | |
| SCHEMBL18843944 | 0.80 | ATM (0.54) | ALOX5AKR1B10AKR1B1APPALDH1A1 | |
| SCHEMBL28517655 | 0.80 | LMNA (0.45) | ALOX5CYP3A4L3MBTL1TBXA2RPTGER3 | |
| SCHEMBL28517659 | 0.80 | LMNA (0.45) | ALOX5CYP3A4L3MBTL1TBXA2RPTGER3 | |
| SCHEMBL28511964 | 0.80 | LMNA (0.56) | ALOX5AKR1B10AKR1B1ALDH1A1HCAR2 | |
| SCHEMBL28511967 | 0.80 | LMNA (0.56) | ALOX5AKR1B10AKR1B1ALDH1A1HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108191656-B | Method for cross dehydrogenation coupling of aromatic carboxylic acid and alpha, beta-unsaturated ester | 陕西师范大学 | 2021-02-02 | — | — | CN | disclosed |