Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | CA4 | P22748 | 2/20 | 0.52 |
| ▸ | CA6 | P23280 | 2/20 | 0.52 |
| ▸ | CA5A | P35218 | 2/20 | 0.52 |
| ▸ | CA7 | P43166 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.52 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.52 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.51 |
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.46 |
| ▸ | PTGER3 | P43115 | 5/20 | 0.45 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28512013 | 1.00 | LMNA (0.56) | LMNAAKR1B10AKR1B1CA12CA4 | |
| SCHEMBL28511964 | 0.90 | LMNA (0.56) | LMNAAKR1B10AKR1B1CA12CA4 | |
| SCHEMBL28511967 | 0.90 | LMNA (0.56) | LMNAAKR1B10AKR1B1CA12CA4 | |
| SCHEMBL28521896 | 0.86 | PTGER3 (0.45) | ALDH1A1ALOX5PTGER3PTGDRPTGER2 | |
| SCHEMBL4480869 | 0.86 | LMNA (0.61) | LMNAAKR1B10AKR1B1CA12CA4 | |
| SCHEMBL28506962 | 0.86 | LMNA (0.61) | LMNAAKR1B10AKR1B1CA12CA4 | |
| SCHEMBL4480867 | 0.86 | LMNA (0.61) | LMNAAKR1B10AKR1B1CA12CA4 | |
| SCHEMBL28521897 | 0.86 | PTGER3 (0.45) | ALDH1A1ALOX5PTGER3PTGDRPTGER2 | |
| SCHEMBL28512002 | 0.84 | ALOX5 (0.47) | AKR1B10AKR1B1HCAR2ALDH1A1ALOX5 | |
| SCHEMBL28516049 | 0.84 | ALOX5 (0.47) | AKR1B10AKR1B1HCAR2ALDH1A1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108191656-B | Method for cross dehydrogenation coupling of aromatic carboxylic acid and alpha, beta-unsaturated ester | 陕西师范大学 | 2021-02-02 | — | — | CN | disclosed |