SCHEMBL28512051

SCHEMBL28512051

Clc1cc2c(Cl)c(Cl)c1COC2

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.34
PRKCG P05129 1/20 0.30
PRKCA P17252 1/20 0.30
PRKCD Q05655 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29026587 0.75 PRKCG (0.37) PRKCGPRKCAPRKCD
SCHEMBL29026589 0.71
SCHEMBL28514559 0.69 KDM4E (0.39) PRKCGPRKCAPRKCD
SCHEMBL25262342 0.66 ALDH1A1 (0.32)
SCHEMBL30743767 0.65 PRKCG (0.31) PRKCGPRKCAPRKCD
SCHEMBL22271601 0.65 GAA (0.50) PRKCGPRKCAPRKCD
SCHEMBL24822237 0.65 PRKCG (0.31) PRKCGPRKCAPRKCD
SCHEMBL22271440 0.65 CD44 (0.41) PRKCGPRKCAPRKCD
SCHEMBL3214971 0.64 ADRA2A (0.42) PNMT
SCHEMBL25164980 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110407663-B Dechlorination method of chlorine-containing aromatic compound 厦门大学 2021-01-26 CN claimed
CN-110407663-B Dechlorination method of chlorine-containing aromatic compound 厦门大学 2021-01-26 CN disclosed