Diethylaniline

Diethylaniline

SCHEMBL28512101

CCN(CC)c1ccccc1.CCO[Si](CCCNC(=O)OCc1ccc(C(=O)O)cc1)(OCC)OCC

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.45
L3MBTL1 Q9Y468 2/20 0.42
MAPT P10636 2/20 0.42
LMNA P02545 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
TGM2 P21980 1/20 0.41
KEAP1 Q14145 2/20 0.40
NFE2L2 Q16236 2/20 0.40
ESRRG P62508 2/20 0.39
ESRRB O95718 1/20 0.39
FOLH1 Q04609 1/20 0.39
HDAC3 O15379 1/20 0.38
HDAC4 P56524 1/20 0.38
HDAC1 Q13547 1/20 0.38
HDAC7 Q8WUI4 1/20 0.38
HDAC2 Q92769 1/20 0.38
HDAC10 Q969S8 1/20 0.38
HDAC11 Q96DB2 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28518922 0.91 ALDH1A1 (0.48) HTTL3MBTL1MAPTLMNASMN1; SMN2
SCHEMBL28520516 0.89 HTT (0.48) HTTL3MBTL1MAPTLMNASMN1; SMN2
SCHEMBL2145355 0.84 HTT (0.62) HTTL3MBTL1MAPTLMNASMN1; SMN2
SCHEMBL17274988 0.83 KMT2A (0.42) HTTL3MBTL1MAPTSMN1; SMN2FAAH
SCHEMBL1546411 0.78 MAPT (0.52) HTTL3MBTL1MAPTLMNASMN1; SMN2
SCHEMBL13789649 0.77 HTT (0.44) HTTL3MBTL1MAPTLMNASMN1; SMN2
SCHEMBL17275002 0.76 ALDH1A1 (0.43) HTTL3MBTL1MAPTSMN1; SMN2FAAH
SCHEMBL9609731 0.76 TGM2 (0.47) HTTL3MBTL1MAPTLMNASMN1; SMN2
SCHEMBL6537376 0.75 HTT (0.44) HTTL3MBTL1MAPTLMNASMN1; SMN2
Diethylaniline SCHEMBL28132292 0.74 ESRRG (0.45) L3MBTL1MAPTLMNASMN1; SMN2ESRRG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106536599-B Methosilylized imine and urethane polymerized benzoate compounds, uses and compositions thereof 因特奎姆私人控股公司 2021-01-12 CN disclosed