Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | TGM2 | P21980 | 1/20 | 0.55 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.54 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.51 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28520516 | 0.88 | HTT (0.48) | HTTLMNASMN1; SMN2TGM2KEAP1 | |
| SCHEMBL6537376 | 0.87 | HTT (0.44) | HTTLMNASMN1; SMN2TGM2KEAP1 | |
| SCHEMBL1546411 | 0.86 | MAPT (0.52) | HTTLMNASMN1; SMN2TGM2KEAP1 | |
| SCHEMBL9609731 | 0.85 | TGM2 (0.47) | HTTLMNASMN1; SMN2TGM2KEAP1 | |
| SCHEMBL13789649 | 0.85 | HTT (0.44) | HTTLMNASMN1; SMN2TGM2KEAP1 | |
| SCHEMBL28518922 | 0.84 | ALDH1A1 (0.48) | HTTLMNASMN1; SMN2TGM2KEAP1 | |
| Diethylaniline SCHEMBL28512101 | 0.84 | HTT (0.45) | HTTLMNASMN1; SMN2TGM2KEAP1 | |
| SCHEMBL1667805 | 0.83 | HTT (0.72) | HTTLMNASMN1; SMN2TGM2KEAP1 | |
| SCHEMBL9609737 | 0.82 | HTT (0.43) | HTTLMNASMN1; SMN2TGM2KEAP1 | |
| SCHEMBL18254066 | 0.82 | HTT (0.81) | HTTLMNASMN1; SMN2TGM2KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6673954-B1 | REACTING AN AMINOORGANOSILANE WITH AN ORGANOCARBONATE ESTER, BASIC CATALYST | GENERAL ELECTRIC COMPANY | 2004-01-06 | — | — | US | claimed |
| US-11236116-B2 | Silicon compound | SK INNOVATION CO., LTD. (KR) | 2022-02-01 | — | — | US | disclosed |
| US-20200331936-A1 | NOVEL SILICON COMPOUND | SK INNOVATION CO., LTD. (KR) | 2020-10-22 | — | — | US | disclosed |
| CN-106488922-B | Process for making low color and color stable isocyanatoorganosilanes and products derived therefrom | 莫门蒂夫性能材料股份有限公司 | 2019-10-11 | — | — | CN | disclosed |
| EP-3169690-B1 | PROCESS FOR PRODUCING LOW-COLOR AND COLOR-STABLE ISOCYANATOORGANOSILANES AND PRODUCTS DERIVED THEREFROM | MOMENTIVE PERFORMANCE MAT INC (US) | 2018-12-05 | — | — | EP | disclosed |
| US-9663539-B2 | Process for producing low-color and color-stable isocyanatoorganosilanes and products derived therefrom | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2017-05-30 | — | — | US | disclosed |
| EP-3169690-A1 | PROCESS FOR PRODUCING LOW-COLOR AND COLOR-STABLE ISOCYANATOORGANOSILANES AND PRODUCTS DERIVED THEREFROM | Momentive Performance Materials Inc. (US) | 2017-05-24 | — | — | EP | disclosed |
| WO-2016010900-A1 | PROCESS FOR PRODUCING LOW-COLOR AND COLOR-STABLE ISOCYANATOORGANOSILANES AND PRODUCTS DERIVED THEREFROM | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2016-01-21 | — | — | WO | disclosed |
| US-20160009738-A1 | PROCESS FOR PRODUCING LOW-COLOR AND COLOR-STABLE ISOCYANATOORGANOSILANES AND PRODUCTS DERIVED THEREFROM | MOMENTIVE PERFORMANCE MATERIALS INC. | 2016-01-14 | — | — | US | disclosed |
| US-20110250254-A1 | ANTIMICROBIAL COMPOSITIONS AND USES | UNIVERSITETET I OLSO (NO) | 2011-10-13 | — | — | US | disclosed |
| US-20110250254-A1 | ANTIMICROBIAL COMPOSITIONS AND USES | UNIVERSITETET I OLSO (NO) | 2011-10-13 | — | — | US | disclosed |
| CN-102215683-A | Antimicrobial compositions and uses | UNI I OSLO | 2011-10-12 | — | — | CN | disclosed |
| EP-2346330-A1 | ANTIMICROBIAL COMPOSITIONS AND USES | Universitetet I Oslo (NO) | 2011-07-27 | — | — | EP | disclosed |
| WO-2010040839-A1 | ANTIMICROBIAL COMPOSITIONS AND USES | UNIVERSITETET I OSLO (NO) | 2010-04-15 | — | — | WO | disclosed |
| US-6673954-B1 | REACTING AN AMINOORGANOSILANE WITH AN ORGANOCARBONATE ESTER, BASIC CATALYST | GENERAL ELECTRIC COMPANY | 2004-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110250254-A1 | ANTIMICROBIAL COMPOSITIONS AND USES | CBR3, C5, C3AR1 | HTT 1409/4885LMNA 4349/4885SMN1; SMN2 4825/4885 |
| US-11236116-B2 | Silicon compound | GRB7, PRMT7, YAP1 | HTT 1896/4885LMNA 4048/4885SMN1; SMN2 1432/4885 |
| US-20200331936-A1 | NOVEL SILICON COMPOUND | PRMT7, CNOT7, GRB7 | HTT 2756/4885LMNA 4268/4885SMN1; SMN2 1934/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.