Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.42 |
| ▸ | PIM1 | P11309 | 3/20 | 0.42 |
| ▸ | PIM3 | Q86V86 | 3/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PRKCA | P17252 | 1/20 | 0.39 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28528175 | 0.84 | ADK (0.47) | IRAK4ALDH1A1HPGD | |
| SCHEMBL21495017 | 0.79 | AR (0.50) | ARPIM1PIM3GAAPIM2 | |
| SCHEMBL26127740 | 0.75 | CCR1 (0.46) | RAB9ANPC1SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL28519673 | 0.72 | LMNA (0.44) | ADORA2AADORA1SMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL2815393 | 0.71 | IRAK4 (0.60) | PIM1PIM3IRAK4GAAPRKCA | |
| SCHEMBL21495084 | 0.70 | MAPT (0.53) | ADORA2AADORA1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL28818217 | 0.69 | SMN1; SMN2 (0.58) | SMN1; SMN2ALDH1A1HPGDKDM4EHTT | |
| SCHEMBL6843345 | 0.68 | GAA (0.59) | GAASMN1; SMN2HSD17B10ALDH1A1HPGD | |
| SCHEMBL16834405 | 0.68 | GAA (0.50) | IRAK4GAANPC1HSD17B10ALDH1A1 | |
| SCHEMBL21495079 | 0.68 | MAPT (0.48) | RAB9ANPC1HSD17B10ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112313229-A | Substituted aminothiazoles as inhibitors of nucleases | 马萨里克大学 | 2021-02-02 | — | — | CN | disclosed |