Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 1/20 | 0.47 |
| ▸ | ATR | Q13535 | 2/20 | 0.46 |
| ▸ | CNR2 | P34972 | 6/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.43 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.43 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28512143 | 0.84 | AR (0.42) | ALDH1A1HPGDIRAK4 | |
| SCHEMBL7370511 | 0.81 | ADK (0.57) | ADKATRCNR2 | |
| SCHEMBL28940962 | 0.76 | ALDH1A1 (0.55) | CNR2ALDH1A1HPGD | |
| SCHEMBL28518770 | 0.73 | LMNA (0.50) | ATRALDH1A1HPGDHDAC6 | |
| SCHEMBL2169026 | 0.72 | CNR2 (0.64) | ADKATRCNR2JAK2ALDH1A1 | |
| SCHEMBL21495029 | 0.71 | MAPT (0.59) | ATRJAK2ALDH1A1 | |
| SCHEMBL6587679 | 0.70 | AURKA (0.53) | ATRCNR2JAK2 | |
| SCHEMBL1246907 | 0.70 | IKBKE (0.57) | ADKATRCNR2JAK2ALDH1A1 | |
| SCHEMBL31436728 | 0.70 | WNT3A (0.39) | JAK2ALDH1A1HPGDIKBKETBK1 | |
| SCHEMBL21495067 | 0.69 | MAPT (0.51) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112313229-A | Substituted aminothiazoles as inhibitors of nucleases | 马萨里克大学 | 2021-02-02 | — | — | CN | disclosed |