Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 11/20 | 0.47 |
| ▸ | KDR | P35968 | 4/20 | 0.47 |
| ▸ | MST1R | Q04912 | 2/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 3/20 | 0.46 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.46 |
| ▸ | HGF | P14210 | 1/20 | 0.45 |
| ▸ | AXL | P30530 | 2/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2335546 | 0.89 | KDR (0.49) | METKDRMST1RPDGFRASRC | |
| SCHEMBL1549776 | 0.87 | MET (0.48) | METKDRMST1RPDGFRASRC | |
| SCHEMBL1549363 | 0.86 | MET (0.43) | METKDRMST1RPDGFRASRC | |
| SCHEMBL28907136 | 0.85 | MET (0.48) | METKDRMST1RPDGFRAAXL | |
| SCHEMBL28530276 | 0.85 | MET (0.45) | METKDRMST1RPDGFRASRC | |
| SCHEMBL1876626 | 0.85 | AXL (0.54) | METKDRPDGFRAAXLPDGFRB | |
| SCHEMBL10296341 | 0.84 | MET (0.42) | METKDRMST1RPDGFRAHGF | |
| SCHEMBL371803 | 0.84 | MET (0.55) | METKDRMST1RPDGFRAHGF | |
| SCHEMBL30713842 | 0.84 | MET (0.55) | METKDRMST1RPDGFRAHGF | |
| SCHEMBL4483017 | 0.84 | MET (0.55) | METKDRMST1RPDGFRAHGF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110357856-B | Arotinib hydrochloride intermediate and preparation method of Arotinib hydrochloride | 新发药业有限公司 | 2021-02-26 | — | — | CN | disclosed |