Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.35 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1156745 | 0.84 | NAPRT (0.42) | NAPRTCYP2C19KDM4EFGFR4MET | |
| SCHEMBL30544721 | 0.83 | NAPRT (0.41) | NAPRTCYP2C19KDM4EFGFR4MET | |
| SCHEMBL3624929 | 0.77 | HTR6 (0.49) | KDM4EMETHDAC1HDAC3HDAC4 | |
| SCHEMBL28711661 | 0.77 | NAPRT (0.41) | NAPRTCYP2C19KDM4EFGFR4MET | |
| SCHEMBL28695918 | 0.77 | KDM4E (0.46) | NAPRTCYP2C19KDM4EMETHPGD | |
| SCHEMBL28558398 | 0.76 | CHRNB2 (0.38) | NAPRTCYP2C19KDM4EFGFR4MET | |
| SCHEMBL29538386 | 0.76 | CHRNB2 (0.38) | NAPRTCYP2C19KDM4EFGFR4MET | |
| SCHEMBL29419678 | 0.75 | FGFR4 (0.39) | NAPRTCYP2C19KDM4EFGFR4MET | |
| SCHEMBL28702432 | 0.75 | FGFR4 (0.39) | NAPRTCYP2C19KDM4EFGFR4MET | |
| SCHEMBL17520466 | 0.74 | HDAC1 (0.42) | NAPRTKDM4EHPGDHDAC1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112300123-B | Preparation method of voronoi intermediate | 上海天慈国际药业有限公司 | 2023-07-18 | — | — | CN | disclosed |
| CN-112300123-A | Preparation method of Vonoprazan intermediate | 上海天慈国际药业有限公司 | 2021-02-02 | — | — | CN | disclosed |